Haina Hot Sale CAS 7361-61-7 Xylazine cannabinoids paura ma

Whakaahuatanga

Ko te Xylazine he agonist o nga kaiwhiwhi α2-adrenergic (Ki = 194 nM).He tairitenga o te clonidine, he agonist kaiawhina α2-adrenergic hei whakaiti i te pehanga toto.Ka whakamahia te Xylazine mo te whakarokiroki, te rewharewha, me te analgesia i roto i nga whakangote kore-tangata.Kei te waatea ano tenei hua hei paerewa tohutoro tātari.
TaketakeXylazine, Bayer

Whakamahinga

Antinociceptive;Alpha-2 agonist adrenergic
Whakamahinga

Ko te Xylazine he karaehe α2 o te agonist adrenergic receptor.Ko te Xylazine he analoque clonidine e mahi ana i runga i nga kaiwhakawhiwhi presynaptic me postsynaptic hei agonist 2-adrenergic.
Tukanga Hangahanga

Ko te 2,6-Dimethylphenyl isothiocyanate, 31.0 g (0.2 mole), i mahia mai i te 2,6- dimethylaniline me te thiophosgene, i taapirihia i roto i te 15 min ki te whakatārewatanga pai o te 15.0 g (0.2 mole) o te 3-aminopropanol-1 i roto i te 100 ml o te etera.I timata te ether ki te koropupu.Ko te whakaoho i raro i te reflux ka haere tonu mo te 30 meneti, katahi ka whakakorehia te ether.Ko te toenga i tukinotia ki te 100 ml o te waikawa pūmāota me te kohuatia i raro i te reflux mo te 30 min.Whai muri i te whakamatao, ka waimeha ki te wai, ka tātarihia kia kore e poke, ka kohia te turanga ma te taapiri o te wairewa konutai konutai.I te rerystallized mai i te benzene-ligroin, ko te hua o te pūhui 2-(2,6- dimethyl-phenylamino)-4H-5,6-dihydro-1,3-thiazine, ira whakarewa 140-142°C (hua 90% o te ariā. ).
Mahi Whakaora

Te whakawhanaunga, te rongoa

Whakaahuatanga Whanui

He wairewa te Xylazine ki te methanol (50 mg/ml), ka puta he otinga maamaa, kore tae.He wairewa ano ki te waikawa HCl waimeha me te chloroform.Ko te Xylazine kare e rewa i roto i te wai me te wairewa kawakore.
Nga Mahi Biochem/physiol

Ko te Xylazine ka whakamahia me te ketamine ka kiia he rongoa kaha me te haumaru i roto i nga kararehe whakamatautau.E mohiotia ana ki te whakanui ake i te tuku ate ate o te huka, e whakararu ana ki te hyperglycemia.
Te tikanga mahi

Ko te Xylazine te hokohoko hei tote hydrochloride hei Rompun (100 mg/mL) me te Anased (20 mg/mL) hei rongoa werohanga mo te whakawhanaunga ki nga hoiho me nga kuri.Ko nga mahi o te xylazine ka taea te huri ma te whakahaere o te yohimbine, he alkaloid indolalkylamine, e aukati ana i aua α2-adrenoreceptors e whakaihiihihia ana e te xylazine.
Kōtaha Haumaru

Te paihana ma te horomia, ki raro i te kiri, ki te ara whakaroto.Nga paanga o te punaha tangata: te huringa o te mahi motika, te heke o te pehanga toto, te miosis, te matotoru o te pleural, te heke o te tere o te pupuhi, te moe.Ina whakamahana ki te pirau, ka puta he paowa tino paitini o NOx me SOx